2型糖尿病血脂异常患者的中医证候学特点探究

目的探讨2型糖尿病血脂异常患者的中医证候分布特点以及2型糖尿病血脂谱与中医辨证分型之间的关系。方法通过对300例2型糖尿病血脂异常患者证候调查,记录一般情况（性别、年龄、身高、体重）,中医证候,总胆固醇（TC）、三酰甘油（TG）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）,进行统计学分析。结果痰湿阻遏证最多105例（35%）,其次是气阴两虚证84例,最少脾肾阳虚证12例（4%）。血瘀脉络证型患者TG升高较其他证型更严重（P〈0.01）;痰湿阻遏型患者TC升高较其他证型严重（P〈0.05）。结论 2型糖尿病血脂异常以痰湿阻遏和气阴两虚两种证型常见,TG增高以气阴两虚为多发,TC增高以痰湿阻遏为多发,在各证型中血瘀脉络和痰湿阻遏血脂值增高明显,因此2型糖尿病血脂紊乱发病主要病因病机可能是气阴两虚、痰瘀内阻。

Study on Characteristics of TCM Syndrome Distribution in the Patient of Type 2 Diabetes Mellitus with Dyslipidemia

To study on characteristics of TCM syndrome distribution and investigate the relationship of lipid profile with TCM syndrome classification in the patient of Type 2 diabetes mellitus with dyslipidemia. Methods A total of 300 patients are enrolled. Each patient record the basic data （gender, age, height, weight）, TCM syndrome, total eholesterol（TC）, triglyceride （TG）,low density lipoprotein cholesterol （LDL-C）, and high density lipoprotein cholesterol （HDL-C）. Then put the data to the statistics analysis. Results The most common type is the syndrome of stagnation of phlegm-dampness（105 cases,35 percent in all of the patients）, The next most common type is the syndrome of deficiency of qi-yin （84 cases）,the rarest type is the syndrome of spleen-kidney yang deficiency（12 cases,4 percent in all of the patients）. The TG in blood stasis in vessel syndrome is higher than others （ P d0.01）. The TC in stagnation of phlegm-dampness syndrome is higher than others （ P d0. 05）. Conclusion The main syndrome types of Type 2 diabetes mellitus with dyslipidemia are deficiency of qi-yin and stagnation of phlegm-dampness. The high TG is common in the syndrome of deficiency of qi-yin,and the high TC is common in the syndrome of stagnation of phlegm-dampness. The blood lipid in the blood stasis in vessel syndrome and stagnation of phlegm-dampness syndrome are higher than others. So the etiology and pathology of Type 2 diabetes mellitus with dyslipidemia are deficiency of qi-yin and stagnation of phlegm-blood stasis.