同种异体原位心脏移植3例临床总结

目的：总结3例同种异体原位心脏移植成功的处理经验，探讨供心保护、免疫抑制剂的应用及感染、预防急性排斥反应等问题。方法：2000年11月和2001年3月先后为终末期肥厚型心肌病、扩张型心肌病和先天性心脏病三尖瓣闭锁行肺动脉环缩术后等3例病人成功地施行了心脏移植手术。术后应用环孢霉素A（CSA）和甲基强的松龙、强的松龙等免疫抑制剂。结果：3例患者已分别生存半年和3个月，心功能正常，生活质量良好。结论：心脏移植、供心保护、吻合技术以及围手术期处理是手术成功的关键。

The Summary of Clinical Experience in Three Cases for Orthotopic Homoplastic Heart Transplantation

Objective To summarize successful experience in three of orthotopic homoplastic heart transplantation,to explore some problems for donor myocardial protection,the application of immunosuppressive drugs,anti-infection and prevent acute rejection.Methods From 2000.11.to 2001.3,we performed successful three cases orthotopic homoplastic heart transplantation;one case of hypertrophic myocardosis in terminal phase, one case of dilatanay myocardosis and one case of geneogenous tricuspic valve atresia.Postoperation,cyclosporin A,methylprednisolone,prednisolone and other immunosuppressive drugs have been used.Results Three patients have survived for three and six months with normal heart function and a good life quality.Conclusion Successful keys of heart transplantation are donor myocardial protection,technology of anastomosis and treatment of peroperation.