| 艾迪注射液联合CT介导射频消融治疗原发性肝癌的临床研究 |
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| 引用本文： | 岳振东,周蕾,刘福全,赵洪伟,王磊. 艾迪注射液联合CT介导射频消融治疗原发性肝癌的临床研究[J]. 中药药理与临床, 2010, 0(2) |
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| 作者姓名： | 岳振东 周蕾 刘福全 赵洪伟 王磊 |
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| 作者单位： | 北京世纪坛医院介入科; |
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| 摘 要： | 目的:观察艾迪注射液联合射频消融术治疗原发性肝癌的疗效、不良反应及其对机体免疫功能等的影响。方法:68例原发性肝癌患者分为治疗组和对照组,对照组给予单纯射频消融治疗,治疗组在射频治疗同时给予艾迪注射液治疗。结果:治疗组及对照组总有效率分别为70.58%和55.88%(P0.01)。两组治疗后丙氨酸转氨酶(ALT)、谷草转氨酶(AST)较治疗前下降(P0.05);两组治疗前后总胆红素(T-BIL)及血清白蛋白(ALB)水平无明显变化。治疗组CD4细胞亚群和CD4/CD8比例治疗后较治疗前增高(P0.05);而单纯射频组CD4细胞亚群和CD4/CD8比例无明显变化。在不良反应方面,消化道反应治疗组显著轻于对照组(P0.01);两组骨髓抑制差异不明显(P0.05)。结论:艾迪注射液联合射频消融治疗原发性肝癌可增强疗效,减轻射频消融对肝功能损害。
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| 关 键 词： | 艾迪注射液 射频消融 原发性肝癌 |
Clinical study on treatment of primary liver cancer by aidi injection combined with radiofrequency ablation |
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| Yue Zhendong,Zhou Lei,Liu Fuquan,Zhao Hongwei,Wang Lei. Clinical study on treatment of primary liver cancer by aidi injection combined with radiofrequency ablation[J]. Pharmacology and Clinics of Chinese Materia Medica, 2010, 0(2) |
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| Authors: | Yue Zhendong Zhou Lei Liu Fuquan Zhao Hongwei Wang Lei |
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| Affiliation: | Yue Zhendong,Zhou Lei,Liu Fuquan,Zhao Hongwei,Wang Lei(Department of interventional therapy,Beijing Shijitan hospital,Beijing 100038) |
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| Abstract: | Objective:To investigate the therapeutic efficacy and adverse reactions of aidi injection combined with percutaneous radiofrequency ablation (CRFA) in treatment of primary liver cancer and to explore its effecton immune function. Methods:68 patients with primary liver cancer were assigned to the control group with CRFA alone and the treatment group treated with CRFA and intravenous dripping of aidi injection. Results:The total effective rate of cancer focus in therapy group and control group were 70.58% and... |
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| Keywords: | aidi injection radiofrequency ablation primary liver cancer |
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