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HBV垂直传播与小儿乙型肝炎关系探讨
引用本文:林国贤,赵汇川,杜庆岭,张光曙.HBV垂直传播与小儿乙型肝炎关系探讨[J].泰山医学院学报,1993(4).
作者姓名:林国贤  赵汇川  杜庆岭  张光曙
作者单位:中国人民解放军88医院,中国人民解放军88医院,中国人民解放军88医院,中国人民解放军88医院
摘    要:报道189例小儿乙肝,按直系亲属有无HBV感染分为阳性组和阴性组。阳性组74例(39.2%),母亲HBsAg阳性51例(68.9%),67.6%为慢性肝炎;阴性组115例(60.8%)父母HBsAg均阴性,15.7%为慢性肝炎。两组差异有非常显著意义(P<0.001)。两组在HBsAg阳性率、阴转率、抗—HBs阳性率、阴转率及HBeAg阳性率也有显著差异。73.4%小儿慢性乙肝与垂直传播有关。提示HBV垂直传播对小儿乙肝诊断和分型有重要意义。

关 键 词:乙型肝炎  垂直传播  儿童

INVESTIGATION OF THE RELATIONSHIP BETWEEN HBV VERTICAL TRANSMISSION AND CHILDREN HEPATITIS B
Lin Guoxian,Zhao Huichuan,Du Qingling,Zhang Guangshu.INVESTIGATION OF THE RELATIONSHIP BETWEEN HBV VERTICAL TRANSMISSION AND CHILDREN HEPATITIS B[J].Journal of Taishan Medical College,1993(4).
Authors:Lin Guoxian  Zhao Huichuan  Du Qingling  Zhang Guangshu
Institution:88th Hospital of PLA
Abstract:189 cases of children hepatitis B were reported. The patients were divided into positive and negative groups according to whether their family have HBV infection. There were 74 patients in positive group(39.2%), among them 67.7% was chronic; 51(68.9%) whose mother's HBsAg was positive. The other 115 patients were in negative group (60.8%), all their parents' HBsAg was negative, only 15.7% was chronic. There was significant difference between the two groups (P<0.001). There was also significant difference in HBsAg positive rate, turn-negative rate, anti-HBs positive rate, turn-positive rate and HBeAg positive rate. Vertical transmission happened in 73.4% of children chronic hepatitis B. There results suggested that HBV vertical transmission play an important role in the diagnosis and classification of children hepatitis B
Keywords:hepatitis B  vertical transmission  children
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