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Identification of a new allele, HLA-DRB1*1360, on a DRB5 haplotype in a Brazilian individual
Authors:Testa G V  Bunce M  Sheldon M H  Dunn P P J  Day S  Marques S B D
Affiliation:Laboratory of Histocompatibility, Hemotherapy Center, University of Campinas, Campinas, Brazil. gvt@obelix.unicamp.br
Abstract:
The application of DNA-based methods for human leukocyte antigen (HLA) genotyping has revealed an ever-increasing degree of polymorphism within the HLA-DRB loci and has resulted in the discovery of new alleles. We have identified a new DRB1 allele that was subsequently named DRB1*1360 by the WHO Nomenclature Committee. This allele is unusual for a DRB1*13 allele, as it is present on a DRB5 haplotype rather than the normal DRB3 haplotype found in association with DRB1*13 alleles.
Keywords:HLA-DRB1*13    PCR-SSP    reverse line PCR-SSO    sequence-based typing
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