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Impact of MELD score in predicting short-term survival after primary liver transplantation
引用本文:Xuewen Ji,Yi Lv,Liang Yu,Shengli Wu,Zheng Wu,Chang Liu,Feng Ma. Impact of MELD score in predicting short-term survival after primary liver transplantation[J]. 南京医科大学学报(自然科学版), 2006, 20(2): 116-119
作者姓名:Xuewen Ji  Yi Lv  Liang Yu  Shengli Wu  Zheng Wu  Chang Liu  Feng Ma
作者单位:Department of Hepatobiliary Surgery, First Hospital,Medical College of Xi' an Jiaotong University, Xi' an 710061, China
摘    要:
Objective: To study the efficacy of model for end-stage fiver disease (MELD) in predicting short-term outcomes in patients undergoing liver transplantation (LT). Methods: The consecutive 62 patients who had received primary LT in our hospital from November 2000 to January 2005 were retrospectively analyzed. The pretransplantafion MELD and Child-Turcotte-Pugh (CTP) scores of these patients were calculated. Concordance c-statistic was used to assess the efficacies of MELD and CTP scores in predicting the first posttransplantation 3-month survival rate. Results: Among the 62 patients receiving primary LT, 12 died during the first 3-month period and the posttransplantation 3-month survival rate was 80.65%. The 3-month survival rate predicted by using CTP score and MELD score was 0.685 and 0.873, respectively. Unlike CTP calssificafion, MELD score indentified two subgroups of patients with CTP C with different overall survival (0.8824 vs 0.4545, ;X^2= 7.00, P = 0.0081 ). Conclusion: Our present study shows that MELD score could offer more accurate prediction for short-term survival in patients who undergo primary LT than CTP score.

收稿时间:2005-12-06

Impact of MELD score in predicting short-term survival after primary liver transplantation
Xuewen Ji,Yi Lv,Liang Yu,Shengli Wu,Zheng Wu,Chang Liu,Feng Ma. Impact of MELD score in predicting short-term survival after primary liver transplantation[J]. Acta Universitatis Medicinalis Nanjing, 2006, 20(2): 116-119
Authors:Xuewen Ji  Yi Lv  Liang Yu  Shengli Wu  Zheng Wu  Chang Liu  Feng Ma
Abstract:
Objective: To study the efficacy of model for end-stage liver disease (MEL D) in predicting short-term outcomes in patients undergoing liver transplantation (LT). Methods: The consecutive 62 patients who had received primary LT in our hospital from November 2000 to January 2005 were retrospectively analyzed. The pretransplantation MELD and Child-Turcotte-Pugh (CTP) scores of these patients were calculated. Concordance c-statistic was used to assess the efficacies of MELD and CTP scores in predicting the first posttransplantation 3-month survival rate. Results: Among the 62 patients receiving primary LT, 12 died during the first 3-month period and the posttransplantation 3-month survival rate was 80.65%. The 3-month survival rate predicted by using CTP score and MELD score was0.685 and 0.873, respectively. Unlike CTP calssification, MELD score indentified two subgroups of patients with CTP C with different overall survival (0.8824 vs 0.4545, χ2 = 7.00, P = 0.0081). Conclusion: Our present study shows that MELD score could offer more accurate prediction for short-term survival in patients who undergo primary LT than CTP score.
Keywords:MELD  Child-Turcotte- Pugh  liver transplantation  survival
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