| 过氧戊二酸对大肠杆菌噬菌体f2杀灭机理 |
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| 引用本文： | 韩益华,涂瀛.过氧戊二酸对大肠杆菌噬菌体f2杀灭机理[J].中国公共卫生学报,1995,14(1):39-40. |
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| 作者姓名： | 韩益华 涂瀛 |
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| 作者单位： | 广州军区防疫队，第三军医大学流行病教研室 |
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| 摘 要： | 观察结果表明过氧戊二酸对大肠杆菌噬菌休ｆ２有较强的杀灭作用，并影响其吸附特性和感染能力。电镜观察表明过氧戊二酸处理后的ｆ２颗粒聚集成团、变形破碎或残缺不全，这可能是ｆ２灭活的主要原因。
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| 关 键 词： | 过氧化戊二酸，大肠杆菌噬菌体f_2，杀灭机理 |
Mechanism of Inactivation of E.coli Bacteriophage f_2 by Perglutaric Acid |
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| Authors: | HanYi hua |
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| Abstract: | Our results suggest that perglutaric acid is an effective disinfectant to entire viruses,and can change the phahg's specific adsorption and in fectivity. By electron microscope, the PGA-treated phage particles became clustered,deformed and fragmentary was observed. The mechanism of inactivation of E. coli phage f2 is mainly by oxidization and destruction of the suspectible amino acids of the capsid proteins. |
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| Keywords: | Peglutaric acid Bacteriophage f_2 Mechaniam of inactivation |
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