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Tolosa-Hunt综合征的临床分析
引用本文:王洋,韩漫夫,任力杰,陈婷. Tolosa-Hunt综合征的临床分析[J]. 中风与神经疾病杂志, 2011, 28(4)
作者姓名:王洋  韩漫夫  任力杰  陈婷
作者单位:深圳市第二人民医院(深圳大学附属第一医院)神经内科,广东,深圳,518035
摘    要:目的 通过回顾性分析Tolosa-Hunt综合征(THS)病例的病因、临床表现、影像学检查结果,为在临床明确诊断该病寻找到有效的方法.方法 对2001年~2009年我院确诊的22例THS患者的临床表现(一般情况、首发症状、脑神经损伤情况)、实验室检查、神经影像学检查结果及治疗方法和预后进行回顾性分析.结果 22例THS患者急性或亚急性起病,头痛首发为主,伴多组颅神经损害,大部分病例病变侧海绵窦有影像学的异常改变.激素治疗有效,治疗后数周至数月内临床症状及影像学异常均明显好转或消失,但可留有颅神经麻痹后遗症及复发.结论 THS患者主要病因考虑为免疫反应有关的非特异性慢性炎症,CT、MRI检查对其确诊有重要价值.根据临床特征、病因及影像学特点进行综合分析,有利于提高诊断率和制定治疗方案.

关 键 词:Tolosa-Hunt综合征  眼肌麻痹  非特异性炎症  海绵窦

Study on the etiology, clinical manifestation and neuroimaging examinations of Tolosa-Hunt syndrome
WANG Yang,HAN Man-fu,REN Li-jie,et al.. Study on the etiology, clinical manifestation and neuroimaging examinations of Tolosa-Hunt syndrome[J]. Journal of Apoplexy and Nervous Diseases, 2011, 28(4)
Authors:WANG Yang  HAN Man-fu  REN Li-jie  et al.
Affiliation:WANG Yang,HAN Man-fu,REN Li-jie,et al.(Department of Neurology,Shenzhen Second People Hospital,the First Affiliated Hospital of University of Shenzhen,Shenzhen 518035,China)
Abstract:Objective To retrospectively study the etiology,clinical manifestation and neuroimaging to make a definite diagnosis of Tolosa-Hunt syndrome(THS).Methods The clinical manifestation(general state of health,first sign,cranial nerve injury),laboratory examination,neuroimaging,remedy and prognosis data of such 22 cases of Tolosa-Hunt syndrome hospitalized from 2001 to 2009 and literatures were retrospectively reviewed.Results 22 patients was acute or subacute onset.First sign was headache and cranial nerves inj...
Keywords:Tolosa-Hunt syndrome  Ophthalmoplegia  Nonspecific inflammation  Cavernous sinus.  
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