不同年龄阶段急性脑梗死患者血清Hcy、hs—CRP、血脂水平表达及意义

目的：分析不同年龄段急性脑梗死患者血清Hcv、hs—CRP、血脂水平表达及意义。方法：选取2010年4月-2013年5月本院急诊收治的270例急性脑梗死患者作为研究对象，根据年龄将所有患者分为青年组40例、中年组105例、老年组125例，另选取健康对照组50例，检测hs—CRP、血清Hcy和血脂水平，分析其相关性。结果：中年组与老年组Hcy、hs—CRP、TC、HDL—C、I,DL—C，青年组Hcv、hs-CRP、HDL—C与对照组水平相比，差异均有统计学意义（P〈0，01）；青中老年组三组中Hcy、hs—CRP、HDL-C检出率均较高，中老年组的LDL—C检出率较高，与其他两组比较差异均有统计学意义（P〈0．01）；不同年龄段急性脑梗死患者间TG、TC、HDL—C、LDL—C呈正相关，HDL—C与hs—CRP呈负相关，hs—CRP与血清Hcy之间未见明显相关性。结论：高血清Hcy是临床急性脑梗死患者的典型独立危险因素，可将其作为临床重要参考指标监测患者病情，辅助临床诊疗。

The Expression and Significance of Hcy,hs-CRP,Blood Lipid Levels in Different Age Stages of Acute Cerebral Infarction

Objective： To analyze the expression and significance of Hcy, hs-CRP, blood lipid levels in different age of acute cerebral infarction.Method： 270 patients with acute cerebral infarction from April 2010 to May 2013 in our hospital were selected, they were divided of the young group for 40 cases, the middle-aged group for 105 cases, the elderly group for 125 cases according to age.And 50 healthy subjects were selected as the healthy control group, the Hey, hs-CRP, blood lipid levels were detected, and analyzed the correlation.Result： The middle-aged group compared with elderly group in Hcy, hs-CRP, TC, HDL-C, LDL-C, and the young group compared with the healthy control group in Hey, hs-CRP, HDL-C, the differences were statistically significant （P〈0.01） .The Hcy, hs-CRP, HDL-C positive rate in the three groups were significantly higher, LDL-C detection rate in the elderly group was the highest, the differences were statistically significant （ P〈0.01 ） .Different age patients with acute cerebral infarction between TG, TC, HDL-C, LDL-C were positively correlated, negatively related to HDL-C and hs-CRP, between hs-CRP and Hcy in serum had no obvious correlation.Conclusion ： High Hcy is a typical independent risk factors of patients with acute cerebral infarction, can be used as an important reference index for monitoring clinical patients, auxiliary clinical diagnosis.