参松养心胶囊对阵发性房颤患者症状及心电图的影响

目的研究参松养心胶囊对阵发性房颤患者症状、体表心电图P波离散度(Pd)、QT间期(QTc)、T波(Tc)、ST段(STc)的影响。方法选择阵发性房颤患者32例,口服参松养心胶囊4周。分别观察治疗前后症状评分及体表心电图Pd、QTc、Tc、STc的变化。结果治疗后症状评分(5.8±2.4)与治疗前(9.1±3.1)比较差异有非常显著意义(P<0.01);治疗后Pd(34±15)ms与治疗前(40±10)ms比较差异有非常显著意义(P<0.01);治疗后QTc(419±32)ms与治疗前(431±35)ms比较差异有显著意义(P<0.05);STc、Tc治疗前后差异无显著意义(P>0.05)。结论参松养心胶囊治疗阵发性房颤可以明显改善症状,同时缩短了Pd、QTc,减轻房室肌复极离散。

The effect of Shensongyangxin capsule on clinical symptoms and ECG in patients with paroxysmal atrial fibrillation

Objective To investigate the effect of Shensongyangxin capsule on clinical symptoms and Pd,QTc,Tc and STc of body surface electrocardiography (ECG) in patients with paroxysmal atrial fibrillation.Methods 32 patients with paroxysmal atrial fibrillation who took Shensongyangxin capsule orally for 4 weeks and then their symptoms marks and Pd,QTc,Tc and STc of ECG were recorded respectively before and after treatment. The Data were analyzed.Results The symptoms marks after treatment were significantly lower than those before treatment (5.8±2.4 vs 9.1±3.1,P<0.01).Pd and QTc of ECG after treatment were significantly lower than those before treatment (34 ms±15 ms vs 40 ms±10 ms,P<0.01;419 ms±32 ms vs 431 ms±35 ms,P<0.05) respectively.There were no significant differences in STc and Tc of ECG before and after treatment (P>0.05).Conclusion The symptoms of patients with paroxysmal atrial fibrillation can be obviously improved and Pd and QTc of ECG are shorted.Meanwhile,repolarization dispersion of cardiac muscle is decreased after patients are treated with Shensongyangxin capsule.