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| 长期尾部悬吊对大鼠左心室乳头肌等长收缩性能的影响 | |
| 引用本文： | 马进 张立藩. 长期尾部悬吊对大鼠左心室乳头肌等长收缩性能的影响[J]. 航天医学与医学工程, 1996, 9(1): 49-53 |
| 作者姓名： | 马进 张立藩 |
| 作者单位： | 第四军医大学航空生理学教研室 |
| 摘 要： | 观察头低位－３０°尾部悬吊１３周对大鼠左室乳头肌等长收缩性能的影响。结果表明，１３周尾部悬吊大鼠左室乳头肌的静息张力与发展张力较同步对照组分别下降１６％和３３％；最大张力速率与最大张力下降速率分别下降３３％和２８％。 |
| 关 键 词： | 失重模拟 等长收缩 乳头肌 心肌收缩 |
Effects of Long-term simulated Weightlessness on Isometric Contractility of Left Ventric-ular Papillary Muscles in Rats |
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| MA Jin. Effects of Long-term simulated Weightlessness on Isometric Contractility of Left Ventric-ular Papillary Muscles in Rats[J]. Space Medicine & Medical Engineering, 1996, 9(1): 49-53 | |
| Authors: | MA Jin |
| Affiliation: | MA JinDepartment of Aerospace Physiology,The Forth Mili-tary Medical University,Xi' an 710032,ZHANG Lifan,YU Zhibin |
| Abstract: | The effects of long-term simulated weightlessness on the,isometric contractile perormance of Papillary muscles isolated from the left ventricle of rats were examined in modified Morey-Holton's tail-suspension rat medel with the technique of iSolated papillary musclc perfusion.The results were as follows:13w tail-suspension cauwesed 33%and 16% decrease in developed tension and resting tension respectively;significant depression in peak rate of tension rise and peak rate of tension decay were also observed;in addition,the concen-tration response curves of extracellular calcium in papillary muscles from 13w tail-suspended rats shifted downward.Thees data indicate that the isometric contractility of papillacy mus-cles from 13 w tail-suspended rats washwered. |
| Keywords: | wweightlessness simulation isemetric contractioh papillacy muscles myocar-dial contraction heart ventricle suspending(hanging) |
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