成人原发性肾病综合征治疗方法探讨

目的：通过临床资料的分析,探讨成人肾病综合征的治疗方法对治疗效果和复发的影响。方法：将１９８８年１月至１９９７年１２月收治的１４６例原发性肾病综合征患者随机分成两组,分别采用三种治疗方案,观察其临床缓解率及复发情况。回顾蛋白尿和生化异常的方法对慢性肾有病型的缓解和减少复法明显好于国内的近期报道。结论不能把注意力一味的放在减少蛋白尿 方面而超剂量应用激素和免疫抑制剂;纠正生化异常可能 远期的动脉硬化

STUDY OF THERAPY FOR THE PRIMARY NEPHROTROTIC SYNDROME IN ADULTS

Objective:To assess the effect of thestrategy of the therapy for nephrotic syndrome on the its recurrence.Methods:The patients with Primary Nephrotic Syndrome were randomly devided into two groups which respectively recevied from Janurary 1988 to december 1998. The clinical data from all cases(n=146) with nephrotic syndrome was collected and analyzed. Results:The improvement of both proteuria and biochemical abnormity stressed in the therapy might increase the rate of remission and decrease recurremce for the nephrotic syndrome. This method was more effective than other methods reported nearly.Conclusion:This study demonstrated that the control of proteuria may not be the index of booster dose of immunodepressive and steroid administrated.The value of correcting biochemical