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顽疣净对复发尖锐湿疣T细胞分泌Th1/TH2细胞因子的影响
引用本文:刘源,侯安继,陆平成. 顽疣净对复发尖锐湿疣T细胞分泌Th1/TH2细胞因子的影响[J]. 武汉大学学报(医学版), 2006, 27(3): 389-391,395
作者姓名:刘源  侯安继  陆平成
作者单位:南京中医药大学,南京,210000;武汉大学中南医院,武汉,430071
摘    要:目的:观察顽疣净含药血清对复发尖锐湿疣(CA)患者外周血T细胞分泌Th1/Th2细胞因子的影响。方法:ELISA法检测顽疣净含药血清对T细胞分泌IL-2I、L-4和IFN-γ的影响。结果:顽疣净能有效提高Th1型细胞因子IL-2和IFN-γ水平,降低Th2型细胞因子IL-4表达。结论:顽疣净含药血清具有调整复发CA患者的Th1/Th2亚群平衡的作用。

关 键 词:中药  顽疣净  复发尖锐湿疣  含药血清  尖锐湿疣  Th1/Th2细胞因子
文章编号:1671-8852(2006)03-0389-03
收稿时间:2005-10-24
修稿时间:2005-10-24

Effect of Wanyoujing Herb Serum on Th1/Th2 Cytokines from T Cells in Peripheral Blood of Relapsing Condyloma Acuminatum Patients
LIU Yuan,HOU Anji,LU Pingcheng. Effect of Wanyoujing Herb Serum on Th1/Th2 Cytokines from T Cells in Peripheral Blood of Relapsing Condyloma Acuminatum Patients[J]. Medical Journal of Wuhan University, 2006, 27(3): 389-391,395
Authors:LIU Yuan  HOU Anji  LU Pingcheng
Affiliation:Nanjing University of Traditional Chinese Medicine, Nanjing 210000, China ;2 Zhongnan Hospital of Wuhan University, Wuhan 430071 , China
Abstract:Objective: To observe the effect of a Chinese herbal drug Wanyoujing herb serum(WYJS) on Th1/Th2 cytokines from T cells in peripheral blood of relapsing condyloma acuminatum patients.Methods: ELISA method was used to measure the cytokines' level of interleukin-2(IL-2),interleukin-4(IL-4) and interferon-γ(IFN-γ) released by T lymphocytes.Results: Wanyoujing herb serum increased levels of Th1 type cytokines(IL-2 and IFN-γ),and inhibited the secretion of Th2 type cytokine(IL-4).Conclusion: Wanyoujing herb serum could regulate Th1/Th2 subgroups' balance,which might play an important role in treating relapsing condyloma acuminatum.
Keywords:Chinese Herbal Drug   Wanyoujing   Herb Serum   Relapsing Condyloma Acuminatum   Th1/Th2 Cytokines
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