Incidence of first onset alcohol use disorder: a 16-year follow-up in the Taiwanese aborigines |
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Authors: | Chau-Shoun Lee Shu-Fen Liao I-Chao Liu Wen-Chung Lee Andrew T. A. Cheng |
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Affiliation: | 1. Department of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan 2. Department of Health Industry Management, Kainan University, Taoyuan, Taiwan 3. Research Center for Genes, Environment and Human Health and Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan 4. Department of Psychiatry, Cardinal Tien Hospital and School of Medicine, Fu Jen Catholic University, Taipei, Taiwan 5. Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
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Abstract: |
Purpose To investigate the incidence and cumulative risk of first onset alcohol use disorder (AUD) in a 16-year follow-up among Taiwanese aboriginal populations. Methods Participants included in this study were cohort subjects free from any AUD at phase 1 survey (n = 428 for DSM-3-R and 451 for DSM-4) of the Taiwan aboriginal study project conducted in 1986–1988. They were reassessed approximately 16 years later, with a response rate of 98.8 %. A Chinese version of the WHO schedules for clinical assessment in neuropsychiatry was employed to assess the lifetime drinking history and AUD. Results Age-standardized annual incidence rates of AUD in all groups were 2.26 and 1.75 % according to DSM-3-R and DSM-4, respectively. The overall incidence rates of AUD were comparable to most of other studies in Caucasian populations, but the sex ratios of women to men were higher in this study (1:2–3) than in the latter (1:6). The incidence of AUD was higher with DSM-3-R than with DSM-4 criteria in this study, attributable to the exclusion of physical/psychological harm in DSM-4 alcohol abuse. The cumulative risks of DSM-4 AUD in this study were very high, being 72.2 ± 19.8 for men and 48.7 ± 8.2 for women up to the age of 65 years. Conclusions High incidence rates and cumulative risks of AUD in Taiwanese aborigines demand effective prevention strategy. |
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