| 黏膜溃疡散的药效学研究 |
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| 引用本文： | 岳 南,只德广,赵益桂,苏 雅.黏膜溃疡散的药效学研究[J].医学教育探索,2010,25(3):198-200. |
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| 作者姓名： | 岳 南 只德广 赵益桂 苏 雅 |
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| 作者单位： | 1 武警医学院生药学教研室，天津市职业与危害生物标志物重点实验室，天津 300162； 2 武警医学院药理学教研室，天津 300162 |
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| 摘 要： | 目的：观察复方低聚原花青素（OPC）的抗疲劳作用。方法：进行复方OPC粉对小鼠游泳时间以及对小鼠血清尿素、血乳酸、肝糖原的影响测定。结果：ig给予复方OPC，能明显延长小鼠游泳时间，降低小鼠血清尿素和血乳酸的量（P＜0.01），而提高肝糖原的量（P＜0.01）。结论：复方OPC能够调整体内代谢，快速恢复体力，是具有明显的抗疲劳作用的新型健康食品。
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| 关 键 词： | 复方低聚原花青素 原花青素 抗疲劳 |
Pharmacodynamics of Nianmo Kuiyang Powder on oral ulcer |
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| YUE Nan,ZHIDe-guang,ZHAO Yi-gui,SU Ya.Pharmacodynamics of Nianmo Kuiyang Powder on oral ulcer[J].Researches in Medical Education,2010,25(3):198-200. |
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| Authors: | YUE Nan ZHIDe-guang ZHAO Yi-gui SU Ya |
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| Institution: | Center for Drug Evaluation and Research, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China |
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| Abstract: | Objective: To study the antifatigue effect of compound pracyanidolic oligomers (OPC). Methods: The effect of compound OPC on swimming time of mice was observed. The effects on the content of the urea, lactatic acid, and liver glycogen were studied, respectively. Results: Compound OPC could enhance the swimming durability of mice.The content of both urea and lactatic acid was decreased, but the content of liver glycogen was increased. Conclusion: Compound OPC has obvious antifatigue effects. The mechanisms maybe associates with increasing the activities of antioxidation enzymes and preventing lipid peroxidation in tissues. |
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| Keywords: | compound pracyanidolic oligomers (OPC) proanthocyanidin antifatigue |
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