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Moving molecular targeted drug therapy towards personalized medicine: issues related to clinical trial design
Authors:Verweij Jaap  de Jonge Maja  Eskens Ferry  Sleijfer Stefan
Affiliation:Erasmus University Medical Center, Daniel den Hoed Cancer Center, s' Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands. j.verweij@erasmusmc.nl
Abstract:
With the event of new Molecular targets, clinical trial design requirements to perform these trials are changing. This paper discusses some of the considerations that need to be taken into account when designing a trial, including those trials that assess combinations of targets.
Keywords:Molecular target   Trial   Design
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