2006年四川省克山病病情调查报告

目的了解和掌握四川省克山病病区病情现状,为四川省克山病预防控制提供科学依据。方法按统一监测方案对选定的冕宁县、西昌市、大竹县监测点内3～70岁常住人口进行问卷调查,临床查体,描记12导联心电图,疑似病例摄2m后前位X线胸片,调查居民经济水平和膳食结构,用荧光法测定人发硒和家庭主食粮食硒的含量。结果3县(市)监测点常住人口1863人,实际调查1672人,受检率为89.75%;临床检出克山病44例,总检出率为2.63%;检出慢型克山病12例,检出率为0.7%;检出潜在型克山病32例,检出率为1.9%;新发并确认亚急型克山病5例;病区居民头发硒均值0.3227mg/kg,大米硒均值0.0201mg/kg,小麦硒均值0.0131mg/kg,玉米硒均值0.010mg/kg。结论四川省仍有潜在型、慢型和亚急型克山病新发病例发生,克山病致病因子在局部地区相对活跃,存在克山病流行的危险。

Investigation on Keshan Disease in Sichuan Province in 2006

Objective To find out the present condition of Keshan disease (KD) and so as to provide scientific evidences for prevention and treatment of KD in Sichuan province. Methods Residents aged from 3 to 70 years old in Mianning county, Xichang city and Dazhu county were investigated based on the uniform surveillance program. Some factors potentially related to KD were also investigated. Results There were 1 863 residents in 3 surveillance sites, and among which 1 672 residents were surveyed, accounting for 89.75% of the population. The number of detectable cases of clinical diagnosis was 44 and the rate was 2.63%. The number of detectable cases of chronic KD was 12 and the rate was 0.7%. The number of detectable cases of latent KD was 32 and the rate was 1.9%. There were 5 people of the new cases of cub-acute KD. The average level of hair selenium was 0.322 7 mg/kg. The average level of rice selenium was 0.013 1 mg/kg. The average level of wheat selenium was 0.013 1 mg/kg and that of corn selenium was 0.010 mg/kg. Conclusions There are still new chronic and latent, cub-acute KD patients. KD is still one of the serious endemic pubic health issues in Sichuan province. The work of KD control and prevention must be strengthened.