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放射性脑病发生的高危因素及MRI影像学改变研究
引用本文:周礼,何文,黄海威. 放射性脑病发生的高危因素及MRI影像学改变研究[J]. 热带医学杂志, 2011, 11(3): 285-287
作者姓名:周礼  何文  黄海威
作者单位:1. 中山大学附属第一医院特诊中心,广东广州,510080
2. 中山大学附属第一医院神经科,广东广州,510080
摘    要:
目的探讨放射性脑病(REP)发生的高危因素和MRI在REP早期诊断中的价值。方法回顾性分析我院近年106例REP患者的临床资料,将发病时间、照射疗程和剂量与MRI影像学检查相结合进行分析。结果 REP发病时间多集中在首次放疗后1~5年,射野上界在OM线上>2.5cm者及生物效应剂量(BED)>139Gy者易发生REP;15.09%的患者尚未出现明显神经系统损害表现时,MRI检查提示为T1WI等或低信号、T2WI高信号。结论对病人采取合理配比照射区域和次数可减少REP的发生,MRI检查有助于早期发现和诊断REP。

关 键 词:放射性脑病  磁共振成像  放射治疗

Role of magnetic resonance imaging iconography in the analysis of radiation encephalopathy and the associated high risk factors
ZHOU Li,HE Wen,HUANG Hai-wei. Role of magnetic resonance imaging iconography in the analysis of radiation encephalopathy and the associated high risk factors[J]. Journal Of Tropical Medicine, 2011, 11(3): 285-287
Authors:ZHOU Li  HE Wen  HUANG Hai-wei
Affiliation:ZHOU Li1,HE Wen1,HUANG Hai-wei2(1.Department of Special Clinic Center,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510008,2.Department of Neurology,China)
Abstract:
Objective To evaluate the use of magnetic resonance imaging iconography in the analysis of radiation encephalopathy.Methods 106 cases of radiation encephalopathy(REP) were retrospectively analyzed.Informations,such as the clinical data,the disease time,irradiation times,irradiation doses and the results of magnetic resonance imaging were studied.Results The development of REP usually occurs at the 1st to 5th year after first radiation,especially when the radiation upper boundary OM line was greater than 2.5...
Keywords:radiation encephalopathy  magnetic resonance imaging  radiation therapy  
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