外周血细胞形态学观察在苯接触工人健康监护和苯中毒诊断的意义

目的 探讨血细胞形态学观察对苯作业工人健康监护和早期预防苯中毒的意义。方法 常规采苯作业工人末梢或静脉血进行ＷＢＣ、ＲＢＣ和ＰＬＴ计数，测定ＨＧＢ浓度，并对ＷＢＣ、ＲＢＣ、ＰＬＴ作形态学观察。结果 在１２０名苯作业工人中共检出３５名异常工人，其中有１８名全血细胞减少；血细胞的形态学改变以中性细胞胞浆出现中毒颗粒和空泡最常见。结论 中性粒出现中毒颗粒和空泡是接触苯后血液系统的早期改变，随后是白细胞减

The value of peripheral blood cytomorphological indexes in health surveillance and poisoning diagnosis among benzene exposed workers

Objective The value of peripheral blood cytomorphology used in health surveillance and poisoning diagnosis for benzene exposed workers was studied.Methods The terminal or vein blood was collected from the benzene exposed workers. The WBC (white blood cell), RBC (red blood cell) and PLT (platelet) were counted. The haemoglobin were determinated. The morphology of WBC, RBC and PLT were observed.Results Of 120 workers who had been exposed to benzene, 35 were abnormal and 18 of them showing decrease of whole blood cell. According to cytomorphology the main changes were the appearances of poisoning gramule and vacuole in the neutrophil cytoplasm.Conclusion It would be an useful index to use peripheral blood cytomorphology for health surveillance and poisoning diagnosis to benzene exposed workers.