1909株铜绿假单胞菌的临床分布及耐药性分析

目的 分析我院住院患者首次分离的1909株铜绿假单胞菌(PA)的临床分布及对19种抗生素的药敏结果,为临床预防感染及指导临床合理用药提供依据.方法 对我院2007年1月～12月首次分离的1909株PA的药敏试验结果和临床分布进行分析.细菌鉴定和药敏试验均采用法国Bio-Merieux公司的VITECK-2全自动微生物分析仪.结果 我院PA感染率前3位的科室为高干病房(38.9%)、神经内科(28.1%)、呼吸内科(19.58%).耐药率最高为复方新诺明(96.3%),其次为四环素(95.3%),耐药率低的有亚胺培南(39.8%)、头孢他啶(29%)、哌拉西林/他唑巴坦(28%)和阿米卡星(14%).结论 目前临床上PA感染以长期卧床的病人或ICU病人为主.治疗上应注意合理应用抗生素,并切断医源性感染的途径.

Clinical Distribution and Antibiotic Resistance of 1909 Stains of Pseudomonas Aeruginosa.

Objective To discuss the clinical distribution and antibiotic resistance of 1909 strains of Pseudomonas aeruginosa(PA)to 19 antibiotics.Methods To collect and isolate clinical specimens from Jan to Dec in 2007,and analysis the drug resistance of 1909 stains of PA.Results The top three departments of infection rnte are Senior Officials inpatient Ward(38.9%),Neurology Department(28.1%)and Pneumology Department(19.58%).The drug with the highest level of antibiotic resistance is Trimethoprin/Sulfa(96.3%),the se...