Identification of a novel allele, B*15012, by polymerase chain reaction using sequence-specific primers (PCR-SSP) and sequence-based typing |
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Authors: | Day S van Dam M Buckland E Dunn P P Ross J |
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Affiliation: | UKTSSA, Stoke Gifford, Bristol, UK. |
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Abstract: | We report here a new allele, B*15012, identified by polymerase chain reaction using sequence-specific primers (PCR-SSP) and sequence-based typing (SBT). B*15012 differs to B*15011 (previously named B*1501) by a single nucleotide, at position 435 of codon 120. B*15011 encodes AAG and B*15012 encodes AAA at codon 120, this difference does not result in an amino acid change. |
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Keywords: | HLA-B HLA-B*15012 HLA-B*15011 sequence-based typing |
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