| RP-HPLC测定宫瘤消片中芍药苷的含量 |
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| 引用本文： | 张迪,马晓璐,张国刚. RP-HPLC测定宫瘤消片中芍药苷的含量[J]. 中国医药导报, 2010, 7(29): 44-46 |
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| 作者姓名： | 张迪 马晓璐 张国刚 |
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| 作者单位： | 1. 辽宁省辽阳市药品检验所,辽宁辽阳,111000
2. 沈阳药科大学,辽宁沈阳,110016 |
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| 摘 要： | 目的：建立高效液相法测定宫瘤消片中芍药苷含量的方法。方法：采用Agilent-C18（4.6mm×150mm,5μm）色谱柱;流动相：乙睛-0.1%磷酸溶液（15∶85）;检测波长：230nm;流速：1.0ml/min。结果：替加氟在0.2～1.0μg范围内与峰面积呈良好的线性关系（r=0.9992）,平均回收率为99.26%,RSD=1.65%（n=5）。结论：本方法简便、准确、重现性好,可用于宫瘤消片中芍药苷的质量控制。
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| 关 键 词： | 宫瘤消片 芍药苷 高效液相色谱法 |
Content determination of Peoniflorin in Gongliuxiao Tablets by RP-HPLC |
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| ZHANG Di,MA Xiaolu,ZHANG Guogang. Content determination of Peoniflorin in Gongliuxiao Tablets by RP-HPLC[J]. China Medical Herald, 2010, 7(29): 44-46 |
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| Authors: | ZHANG Di MA Xiaolu ZHANG Guogang |
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| Affiliation: | 1.Institute for Drug Control of Liaoyang City, Liaoyang 111000, China; 2.Shenyang Pharmaceutical University, Shenyang, 110016 China) |
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| Abstract: | Objective： To establish a method for the content determination of Peoniflorin in Gongliuxiao Tablets by HPLC. Methods： The Agilent-C18 （4.6 mm×150 mm, 5 μm） column was used. The mobile phases consisted of acetonitrile and 0.1%-phosphoric acid （15∶85）, the flow rate was 1.0 ml/min and the detection wavelength was at 230 nm. Results： The linear ranges of Peoniflorin was at 0.2-1.0 μg （r=0.999 7）, the average recovery was 99.70% with a RSD of 1.65% （n=5）. Conclusion： The method is fast, reliable, accurate and can be used in the quality control of Peoniflorin in Gongliuxiao Tablets. |
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| Keywords: | Gongliuxiao Tablets Peoniflorin RP-HPLC |
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