Abstract: | Activity of 3-OH-steroid dehydrogenase in the adrenal cortex of 21-day rat fetuses in the control and 3 days after decapitationin utero was estimated quantitatively by microspectrophotometry. Activity of the enzyme, calculated per conventional cell in the zona fasciculata was considerably higher than in the developing zona glomerulosa. After hypophysectomy the 3-OH-steroid dehydrogenase activity was reduced in both zones of the adrenal.Laboratory of Hormonal Regulation and Laboratory of Cytology, Institute of Developmental Biology, Academy of Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 11, pp. 1317–1320, November, 1976. |