帕罗西汀联合逍遥散治疗抑郁症对照研究

目的探讨帕罗西汀联合逍遥散治疗抑郁症的临床疗效。方法将76例抑郁症患者随机分为两组各38例，两组均口服帕罗西汀治疗，研究组联合逍遥散治疗，观察8周。于治疗前及治疗第2周、4周、8周末用汉密尔顿抑郁量表（HAMD）评定临床疗效。结果观察组有效率为97．36％，对照组为81．57％，二者有显著性差异（P〈0．05）。两组治疗前HAMD无显著性差异，治疗8周末均较治疗前显著下降（P〈0．01），但研究组较对照组下降明显（P〈0．05）。结论帕罗西汀联合逍遥散治疗抑郁症疗效显著。

A contrast study of Paroxetine combined with Xiao Yao San in the Depression

Objective To observe the efficacy of Paroxetine combined with Xiao Yao San in the Depression.Methods 6 patients were randomly divided into two groups of 38,both groups took orally Paroxetine and research group was added Xiao Yao San for 8 week.Effects were assessed with the Hamilton Depression Scale(HAMD)before treatment and at the end of the 2 nd ,4th,and 8th week treatment.Results The effective rate was respectively 97.36% in the research and 81.57% in the control group ,which showed have significant different(P ＜ 0.05).Before treatment,there were no significant different in the Hamilton Depression Scale (HAMD),and those of both groups lowered more significantly at the end of the 8th week compared with pretreatment(P ＜ 0.01),so did in the research(P ＜ 0.05).Conclusion Paroxetine combined with Xiao Yao San have an significant effect in the treatment of Depression.