米索前列醇配合缩宫素减少剖宫产术后出血的临床观察

目的：观察米索前列醇配合缩宫素在减少剖宫产术后出血中的作用。方法：将100例有发生产后出血高危因素的剖宫产孕妇，随机分为两组，观察组在胎儿娩出后用米索前列醇配合缩宫素刺激宫缩，对照组在胎儿娩出后单纯用缩宫素刺激宫缩。观察两组术中及产后2h内出血量。结果：观察组平均出血量为（234．6±86．6）ml，对照组为（316．0±148．9）ml，组间差异有统计学意义（P〈0.05）。结论：与单纯使用缩宫素相比，在剖宫产中米索前列醇配合缩宫素使用可以更有效地减少产后出血。

Clinical observation of Misoprostol combinded with Oxytocin on reducing cesarean section bleeding

Objective： To observe the function of Misoprostol eombinded with Oxytocin on reducing cesarean section bleeding. Methods： 100 eases of section pregnant woman who had high risk of postpartum hemorrhage were randomized into two groups. After expulsion of fetus, pregnant woman in observation group was injected with Misoprostol combinded with Oxytoein for uterine contraction, pregnant woman in control group was injected simply with Oxytocin for uterine contraction. We observed the amount of bleeding in surgery and post-natal two hours of both group. Results： The mean amount of bleeding was （234.6±86.6） ml in observation group, while （316.0±148.9） ml in control group, the difference was significant. Conclusion： Misoprostol combined with Oxytocin is more effective on reducing of postpartum hemorrhage than Oxytocin.