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Epidermal growth factor: the driving force in initiation of RPE cell proliferation |
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| Authors: | Kerstin Steindl-Kuscher Michael E. Boulton Paulina Haas Astrid Dossenbach-Glaninger Hans Feichtinger Susanne Binder |
| Affiliation: | (1) Department of Ophthalmology, Ludwig Boltzmann Institute for Retinology and Biomicroscopic Lasersurgery, Rudolf Foundation Clinic, Juchgasse 25, 1030 Vienna, Austria;(2) Department of Anatomy and Cell Biology, University of Florida, Gainesville, FL, USA;(3) Department of Clinical Chemistry, Rudolf Foundation Clinic, Vienna, Austria;(4) Department of Pathology and Bacteriology, Rudolf Foundation Clinic, Vienna, Austria |
| Abstract: | BackgroundTo analyze whether epidermal growth factor (EGF) exerts regulatory effects on proliferation and differentiation in ARPE19 cells after different incubation periods (24 vs. 48 h) for obtaining ideal conditions for feasible rejuvenation and autologous transplantation of retinal pigment epithelial cells (RPE cells). |
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