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A single mutation causes a spectrum of cardiovascular defects: the potential role of genetic modifiers, epigenetic influences, and stochastic events in phenotypic variability |
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| Authors: | Black Brian L |
| Affiliation: | Cardiovascular Research Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, Genentech Hall, 600 16th Street, San Francisco, CA 94143-2240, USA |
| Abstract: | |
| Keywords: | CHF1 Hey2 Gridlock Hrt2 Hesr2 Sox10 Tbx1 Tbx5 Epigenetic Genetic modifiers Ventricular septal defect VSD Outflow tract Mouse Developmental noise Stochastic BALB/c C57BL/6 Hirschsprung DiGeorge Holt-Oram |
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