| 阿德福韦酯结合拉米夫定对慢性乙型肝炎肝硬化的疗效探讨 |
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| 引用本文： | 朱林昌. 阿德福韦酯结合拉米夫定对慢性乙型肝炎肝硬化的疗效探讨[J]. 中国医药指南, 2011, 9(36): 51-52 |
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| 作者姓名： | 朱林昌 |
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| 作者单位： | 深圳口岸医院消化科,广东,深圳,510280 |
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| 摘 要： | 目的探讨阿德福韦酯结合拉米夫定对慢性乙型肝炎肝硬化的疗效。方法对我院125例慢性乙型肝炎肝硬化患者分别采用单药和结合药物进行治疗,对其HBV DNA阴转率及HBeAg阴转率和肝纤维化指标进行检测分析。结果结合组HBV DNA阴转率及HBeAg阴转率均较单药组高;结合组患者治疗前后的纤维化指标差异明显,且差异较单药组显著。结论阿德福韦酯结合拉米夫定对慢性乙型肝炎肝硬化的疗效明显优于单用阿德福韦酯或拉米夫定,在临床上值得广泛应用。
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| 关 键 词： | 阿德福韦酯 拉米夫定 慢性乙型肝炎肝硬化 |
Clinical Analysis of the Treatment of CHB by Adefovir Dipivoxil Combined with Lamivudine |
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| ZHU Lin-chang. Clinical Analysis of the Treatment of CHB by Adefovir Dipivoxil Combined with Lamivudine[J]. Guide of China Medicine, 2011, 9(36): 51-52 |
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| Authors: | ZHU Lin-chang |
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| Affiliation: | ZHU Lin-chang (Department of Gastroenterology, Shenzhen Port Hospital, Shenzhen 510280, China) |
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| Abstract: | Objective Clinical analysis of the treatment of CHB by Adefovir dipivoxil combined with lamivudine. Methods The hospital 125 cases of CHB patients with single drug and combination drug therapy, the negative transforming rate ofHBV DNA, negative conversion rate ofhbeag, liver fibrosis indexes were determined respectively. Results The combination group＇s HBV DNA negative conversion rate and HBeAg negative conversion rate are higher than the single group; combined group of liver fibrosis indexes significant after treatment, and significantly higher than single-drug group. Conclusion Adefovir dipivoxil combined with lamivudine for CHB was significantly better than adefovir dipivoxil alone or lamivudine, could be widely used in clinical practice. |
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| Keywords: | Adefovir dipivoxil Lamivudine CHB |
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