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高强度聚焦超声对恶性肿瘤患者细胞免疫功能的影响
引用本文:黄耀,张卫星,彭淮都,魏杨辉,陈小珍. 高强度聚焦超声对恶性肿瘤患者细胞免疫功能的影响[J]. 中国热带医学, 2010, 10(4): 488-489
作者姓名:黄耀  张卫星  彭淮都  魏杨辉  陈小珍
作者单位:广东医学院附属深圳福田医院肝胆外科,广东深圳,518000
摘    要:
目的探讨高强度聚焦超声(HIFU)对恶性肿瘤患者细胞免疫功能的影响。方法取52例恶性肿瘤患者HIFU治疗前和治疗后7d外周血2ml,用流式细胞仪检测NK、rdT、CD4+T、CD8+T细胞百分数和CD4+/CD8+。结果经HIFU治疗后患者的NK细胞、rdT细胞百分数显著升高(P0.05),CD4+T细胞百分数和CD4+/CD8+比值明显升高(P0.05),CD8+T细胞百分数则下降(P0.05)。结论HIFU既能非侵入性、微创、准确、适形灭活肿瘤,又能提高恶性肿瘤患者机体内的细胞免疫功能。

关 键 词:高强度聚焦超声(HIFU)  恶性肿瘤  细胞免疫

Effect of high intensity focused ultrasound on cellular immune function of patient with malignant tumor.
HUANG Yao,ZHANG Wei-xing,PENG Huai-du,et al.. Effect of high intensity focused ultrasound on cellular immune function of patient with malignant tumor.[J]. China Tropical Medicine, 2010, 10(4): 488-489
Authors:HUANG Yao  ZHANG Wei-xing  PENG Huai-du  et al.
Affiliation:HUANG Yao,ZHANG Wei-xing,PENG Huai-du,et al.(The Futian Hospital Affiliated to Guangdong Medical College,Shenzhen 518000,Guangdong,P. R. China)
Abstract:
Objective To investigate the effect of high intensity focused ultrasoUndon on cellular immune function of. patients with malignant tumor. Methods The levels of NK,rdT,CD4^+T,CD8^+T in 52 malignant tumor cases under HIFU treatment before and seven days after treatment were determined by flow cytometry. Results After treatment the levels of NK cells, rdT cell, CD4^+T cell and the ratio of CD4^+/CD8^+ were significantly increased (P〈0.05). While the level of CD8^+T cell decreased (P〈0.05). Conclusions HIFU is a non-invasive, minimally trauma, accurate, conformal tumor-inactivated method,it can also enhance the cellular immune function of patients with malignant tumor.
Keywords:High intensity focused ultrasound  Malignant tumor  Cellular immune  
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