乳腺腺纤维瘤10316例临床病理分析

 自1954～1990年36例间共收治乳腺腺纤维瘤10316例，均接受手术治疗并经病理证实，其中管型腺纤维瘤3436例占33．3％，围管型腺癌2795例占27．1％，混合型腺纤维瘤3156例占30．6％，分叶型腺纤维瘤526例占5．1％，囊性增生型腺纤维瘤403例占3．9％。患病年龄从9岁～68岁，中位年龄28岁。2／3在发病后2年内就诊。肿瘤最小0．3cm，最大24cm（仅1例，为分叶型腺纤维瘤），大多数≤3cm，占66．5％。病变绝大多数为单发，9228例，占89．5％，多发或双发的1088例，占10．5％。绝大多数经局部切除后治愈，少数病例433例（4．2％）切除后又复发，经再次切除治愈。在收治10316例乳腺腺纤维瘤的同期内有4例腺纤维瘤癌变为管内癌，经手术切除后，预后良好。

Breast Fibroadenoma

Between 1954 and 1990, 10316 patients with breast fibroadenoma were treated and proved by pathology, among which intraductal fibroadonoma(3436 cases) made up to 33.3%, periductal fibroadenoma (2795 cases) 27.1%, mixed type fibroadenoma (3156 cases) 30.6%, lobulated fibroadenoma (526 cases) 5.1% and cystic hyporplastic fibroadenoma (403 cases) 3. 9% respectively.Ages of patients ranged from 9 to 68 years old.with the modian age of 28 years old. 2/3 patients were treated within 2 years after symptom presented.Tumor size ranged from 0. 3cm to 24cm, most of which (66. 5%) were smaller than 3cm.Solitary tumor was detected in 9228 cases (89.5%), and two or multiple tumors were detected in 1088 cases (10.5%).Most patients were cured by lumpectomy, while 433 patients (4.2%) recurred and were cured after resection again. Only 4 cases of carcinoma arising which were intraductal carcinoma were detected among all patients, of which prognosis was good after mastectomy.