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原发性肝癌并发门静脉癌栓临床探讨
引用本文:翁敬飚,阮海兰,韦玲,李佳. 原发性肝癌并发门静脉癌栓临床探讨[J]. 重庆医学, 2010, 39(17). DOI: 10.3969/j.issn.1671-8348.2010.17.044
作者姓名:翁敬飚  阮海兰  韦玲  李佳
作者单位:海南省农垦总医院消化内科,海口,570203;海南省农垦总医院消化内科,海口,570203;海南省农垦总医院消化内科,海口,570203;海南省农垦总医院消化内科,海口,570203
摘    要:目的探讨原发性肝癌(PHC)并发门静脉癌栓(PVTT)的临床特点。方法回顾性分析该院自2001年至2010年300例PHC并发132例PVTT患者的临床资料,总结年龄、性别、肝硬化、乙型肝炎表面抗原(HBsAg)、肿瘤类型、生化指标、甲胎蛋白(AFP)、凝血酶原时间(PT)等相关因素及癌栓发生的部位与PVTT的相关性。结果 300例PVC中合并PVTT132例(44%)。其中40~60岁年龄组、弥漫型病灶、有腹水患者发病率较高,与其他组比较差异有统计学意义。肝硬化、HBsAg阳性、PT延长、AFP增高、清蛋白(Alb)降低,总胆红素(TBIL)>22是相关危险因素。癌栓好发部位在门静脉主干,发病率为68.9%。结论 PHC合并PVTT易发生于腹水患者、HBsAg阳性、有肝硬化基础、弥漫型病灶的中年男性,肝脏储备功能差是其危险因素,好发部位为门静脉主干。

关 键 词:原发性肝癌  门静脉癌栓  临床特点

Observation of clinical characteristics of primary hepatic cancer with portal vein tumor thrombus
WENG Jing-biao,RUAN Hai-lan,WEI Ling,et al.. Observation of clinical characteristics of primary hepatic cancer with portal vein tumor thrombus[J]. Chongqing Medical Journal, 2010, 39(17). DOI: 10.3969/j.issn.1671-8348.2010.17.044
Authors:WENG Jing-biao  RUAN Hai-lan  WEI Ling  et al.
Affiliation:WENG Jing-biao,RUAN Hai-lan,WEI Ling,et al.(Department of Gastroenterology,Agricultural Reclamation General Hospital of Hainan Provincial,Haikou 570203,China)
Abstract:Objective To investigate the clinical characteristics of primary hepatic cancer(PHC)with portal vein tumor thrombi(PVTT).Methods Clinical data of 132 patients with PVTT in 300 patients with PHC were analysed retrospectively from 2001 to 2010.Age,sex,cirrhosis,HBsAg.tumor type,biochemical markers,alpha-fetoprotein(AFP),prothrombin time(PT) and other relevant factors and location of cancer embolus were summarized to study its relativity with PVTT.Results There were 132 patients(40.4%) with PVTT in 300 patient...
Keywords:primary hepatic cancer  portal vein tumor thrombus  clinical features  
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