胃肠道癌手术与门静脉单细胞转移的相关性研究

目的 进一步了解在胃癌、大肠癌的根治过程中,手术对单细胞转移的影响。方法 １７２例２分２组,阳性受检组１１１例,先结扎肿瘤区引渡以血和的阴性对照组６１例。开腹探后将导管置入门静脉抽取血标本,抗上皮细胞膜克隆抗体为探针,ＡＢＣ免疫组化法检测门静脉癌细胞。结果 阳性受检组１１１例患者中有７２例发现肿瘤细胞、阳性率为６４．９％,有性对照组的６１例仅发现１３例,阳性率为２１．３％,两组且间差异有显著性,

The relationship between operation on gastrointestinal cancer and single cells metastasis via portal vein

Objective To confirm the effect of radical operation on single cells metastasis of gastrointestinal cancer. Methods One hundred and seventy two patients with gastrointestinal cancer were divided randomly into group (111 cases,ordinary operation) and group (61 cases,operation after ligation of drained vessels). Catheters were inseted into the portal vein during operation.Blood was aspriated and contrifugated.AntiEMA monocolonal antibody marked the cancer cells, which were shown by ABC immunohistochemical stainning. ResultsWT5BZIn the examinated group, 72 cases of gastreintestinal cancer were found positive cells among 111 cases(positive rate 649%).In the control group,61 cases were tested and 13 cases were found positive cells(posititve rate 213%) with a highly significant difference between the two groups(P<0005). Conclusions Ligating the relative blood vessel before the radical operation can prevent single cancer cells from metastasis via portal vein.