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Expression of B7-1 and B7-2 mediated by adenovirus enhanced T cell anti-hepatoma immunity
摘    要:
The ultimate aim of cancer immunotherapy is theinduction of tumor-specific T-lymphocyte responseseffective in eradicating disseminated tumors. There aregenerally tumor infiltrating T lymphocytes in situ oftumor, but most of which are inactive, one of the majorreasons of such Inactivation is that T lymphocytes areexposured to an antigen-specific TCR signal in theabsence of antigen-nonspecific or co-stimulatory signal.The co-stimulatory factors, B7-l and B7-2 on the surfaceof antigen presenting cells provide a key signal for thegeneration of T cell immunity. Sincc hepatoma usually

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