| MELD评分评估血浆置换治疗慢性乙型重型肝炎的疗效 |
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| 引用本文： | 刘雯. MELD评分评估血浆置换治疗慢性乙型重型肝炎的疗效[J]. 实用肝脏病杂志, 2011, 14(1): 29-30. DOI: 10.3969/j.issn.1672-5069.2011.01.010 |
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| 作者姓名： | 刘雯 |
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| 作者单位： | 第二人民医院肝病一科,安徽省阜阳市,236015 |
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| 摘 要： | 目的应用终末期肝病模型（MELD）评价血浆置换（PE）治疗慢性乙型重型肝炎的临床疗效。方法对112例慢性乙型重型肝炎患者进行PE治疗,检测总胆红素、国际标准化比值和肌酐水平以计算MELD分值。按照治疗前患者MELD分值〈30分、30～40分和≥40分分成三组,观察各组3个月内的病死率。结果 PE治疗后112例患者血生化指标改善;3个月内,在MELD评分〈30的63例患者中,死亡12例（19%）;在30≤MELD评分〈40分的34例患者中,死亡20例（58.8%）;在MELD评分≥40分的15例患者中,死亡15例（100%,P〈0.05）。结论 MELD评分系统能预测PE治疗慢性乙型重型肝炎患者的预后。
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| 关 键 词： | 慢性乙型肝炎 重型肝炎 血浆置换 终末期肝病模型 |
Model for end-stage liver disease to predict survival in patients with chronic severe hepatitis B |
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| LIU Wen. Model for end-stage liver disease to predict survival in patients with chronic severe hepatitis B[J]. Journal of Clinical Hepatology, 2011, 14(1): 29-30. DOI: 10.3969/j.issn.1672-5069.2011.01.010 |
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| Authors: | LIU Wen |
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| Affiliation: | LIU Wen.Department of Liver Disease,Second Municipal People's Hospital,Fuyang 236015,Anhui Province,China |
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| Abstract: | Objective To evaluate the value of model for end-stage liver disease(MELD)scoring system in predicting the prognosis of patients with chronic severe hepatitis B receiving plasma exchange.Methods Total serum bilirubin,international normalized ratio and creatinine were determined pre-treatment and post-treatment in 112 patients with chronic severe hepatitis B who were treated with plasma exchange.The patients were divided into three groups according to MELD score.The mortality rate within three months post-tr... |
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| Keywords: | Chronic hepatitis B Severe hepatitis Plasma exchange Model for end-stage liver disease scoring system |
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