立体定向放射治疗原发性肝癌伴下腔静脉癌栓的疗效评价

目的评价立体定向放疗治疗肝细胞癌伴下腔静脉癌栓的疗效。方法在66例肝细胞癌伴下腔静脉癌栓患者中,36例接受立体定向放射治疗,30例未接受放射治疗。结果 36例接受伽玛刀治疗的癌栓患者,12例（33.3%）癌栓完全缓解,10例（27.8%）部分缓解,13例（36.1%）稳定,1例（2.8%）进展。癌栓治疗有效率为61.1%,1年生存率为27.8%,中位生存期为9.8个月;未放疗的30例患者1年生存率为11.5%,中位生存期为3.5个月。多因素分析显示,放疗组病人生存情况与肝内病灶单多发有关。Child-Pugh分级是影响预后的主要因素。结论立体定向放射治疗可明显延长肝细胞癌伴有下腔静脉癌栓患者的生存期。

Efficacy of stereotactic conformal therapy in the treatment of patients with hepatocellular carcinoma with tumor thrombus in inferior vena cava

Objective To evaluate the effects of stereotactic conformal therapy(SCT)in the treatment of patients with hepatocellular carcinoma with tumor thrombus in inferior vena cava.Methods 66 hepatocellular carcinoma patients with tumor thrombus in inferior vena cava were reviewed and analyzed by Kaplan-Meier and Cox regression analysis.36 patients with tumor thrombus in inferior vena cava with hepatocellular carcinoma were treated with stereotactic conformal therapy(body gamma knife),and 30 patients did not receiv...