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兴安藜芦乙酸乙酯部位化学成分的研究
引用本文:聂利月,汤建,李慧梁,金慧子,张卫东. 兴安藜芦乙酸乙酯部位化学成分的研究[J]. 中国药学杂志, 2008, 43(13): 971-973
作者姓名:聂利月  汤建  李慧梁  金慧子  张卫东
作者单位:1.上海交通大学药学院 上海 200240;2.第二军医大学药学院 上海 200433
基金项目:上海市登山计划重大项目
摘    要:
 目的对百合科藜芦属植物兴安藜芦乙酸乙酯部位的化学成分进行研究。方法采用柱色谱分离,通过理化和波谱分析方法鉴定化合物的结构。结果从其乙酸乙酯部位分离得到6个化合物,经理化与波谱分析鉴定,分别为veramitaline (Ⅰ),计明碱(Ⅱ),藜芦托素(Ⅲ),伪介芬胺(Ⅳ),白藜芦醇苷(Ⅴ),mulberroside A(Ⅵ)。结论化合物Ⅰ~Ⅱ,Ⅳ~Ⅵ为首次从该植物中分得,其中化合物Ⅵ是首次从该属植物中分得。

关 键 词:兴安藜芦  藜芦托素  伪介芬胺  白藜芦醇苷  mulberrosideA
收稿时间:2007-09-10;

Studies on Chemical Constituents of Acetyl Acetate Extracted Fraction from Veratrum dahuricum
NIE Li-yue,TANG Jian,LI Hui-liang,JIN Hui-zi,ZHANG Wei-dong. Studies on Chemical Constituents of Acetyl Acetate Extracted Fraction from Veratrum dahuricum[J]. Chinese Pharmaceutical Journal, 2008, 43(13): 971-973
Authors:NIE Li-yue  TANG Jian  LI Hui-liang  JIN Hui-zi  ZHANG Wei-dong
Affiliation:1.School of Pharmacy,Shanghai Jiaotong University,Shanghai 200240,China;2.School of Pharmacy,Second Military Medical University,Shanghai 200433,China
Abstract:
OBJECTIVE To study the chemical constituents of acetyl acetate extracted fraction from Veratrum dahuricum. METHODS The compounds were isolated and purified by silica,Sephadex LH-20 and polyamide column chromatography and their structures were identified by physicochemical properties and spectral analysis.RESULTS Six compounds were isolated and identified as veramitaline(Ⅰ),germine(Ⅱ),veratrosine(Ⅲ),pseudojervine(Ⅳ) piceid(Ⅴ),mulberroside A(Ⅵ).CONCLUSION CompoundⅠ-ⅡandⅣ-Ⅵare isolated from V.dahuricum for the first time,and compoundⅥis firstly obtained from this genus.
Keywords:Veratrum dahuricum')"   href="  #"  >Veratrum dahuricum  veratrosine')"   href="  #"  > veratrosine  pseudojervine  piceid  mulberroside A
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