Phase II study of bleomycin,actinomycin D,DTIC and vindesine in disseminated malignant melanoma |
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| Affiliation: | 1. Division of Medical Oncology, Department of Internal Medicine, University Hospital, Groningen, The Netherlands;2. Department of Oncological Surgery, University Hospital, Groningen, The Netherlands |
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| Abstract: | ![]()
Twenty-seven patients with disseminated malignant melanoma were treated with combination chemotherapy consisting of bleomycin, actinomycin D, DTIC and vindesine. There were 4 complete responses in patients with pulmonary metastasis, 5 patients had a partial remission, 2 of them had mainly lung lesions. Toxicity consisted mainly of leuco- and thrombocytopenia of short duration and sporadic severe mucositis. |
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