| 急性动脉粥样硬化性脑梗死患者血清脑红蛋白水平的意义 |
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| 引用本文： | 赵守财,储照虎.急性动脉粥样硬化性脑梗死患者血清脑红蛋白水平的意义[J].中国神经再生研究,2011,6(27):2140-2145. |
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| 作者姓名： | 赵守财 储照虎 |
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| 作者单位： | 安徽省芜湖市皖南医学院弋矶山医院神经内科,安徽省芜湖市皖南医学院弋矶山医院神经内科 |
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| 基金项目： | 安徽省科技计划项目：脑血管疾病患者血压与颅内压管理的临床研究（计划编号：08020304111）。 |
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| 摘 要： | This study sought to examine neuroglobin (NGB) in the serum of acute cerebral infarction patients with double-antibody sandwich enzyme-linked immunosorbent assay to identify all risk factors, calculate infarct size, assess neurological impairment, and analyze the relation between NGB and each of these factors. The double-antibody sandwich assay indicated that levels of NGB in serum were unaltered within 6 hours following acute cerebral infarction compared with normal levels. NGB levels then underwent a distinct change, peaking at 24 hours then returning to normal levels in 72 hours. The results suggest that the level of NGB might be related to infarct size and low-density lipoprotein at 24 hours after acute cerebral infarction. There were no significant differences in neurological impairment scores and infarct size at different periods following infarction. The findings indicated that the level of NGB in serum of acute cerebral infarction patients was correlated with infarct time.
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| 关 键 词： | neuroglobin acute cerebral infarction onset time morbidity infarct size neurological impairment score |
Significance of neuroglobin in serum of acute atherosclerotic cerebral infarction patients |
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| Shoucai Zhao,Zhaohu Chu,Lingsong Ma,Yinong Chen,Lei Wang,Benxiao Wang,Zili Huang,Jun Zhang.Significance of neuroglobin in serum of acute atherosclerotic cerebral infarction patients[J].Neural Regeneration Research,2011,6(27):2140-2145. |
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| Authors: | Shoucai Zhao Zhaohu Chu Lingsong Ma Yinong Chen Lei Wang Benxiao Wang Zili Huang Jun Zhang |
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| Institution: | Shoucai Zhao,Zhaohu Chu,Lingsong Ma,Yinong Chen,Lei Wang,Benxiao Wang,Zili Huang,Jun Zhang Department of Neurology,Yijishan Hospital,Wannan Medical College,Wuhu 241001,Anhui Province,China |
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| Abstract: | This study sought to examine neuroglobin (NGB) in the serum of acute cerebral infarction patients with double-antibody sandwich enzyme-linked immunosorbent assay to identify all risk factors, calculate infarct size, assess neurological impairment, and analyze the relation between NGB and each of these factors. The double-antibody sandwich assay indicated that levels of NGB in serum were unaltered within 6 hours following acute cerebral infarction compared with normal levels. NGB levels then underwent a distinct change, peaking at 24 hours then returning to normal levels in 72 hours. The results suggest that the level of NGB might be related to infarct size and low-density lipoprotein at 24 hours after acute cerebral infarction. There were no significant differences in neurological impairment scores and infarct size at different periods following infarction. The findings indicated that the level of NGB in serum of acute cerebral infarction patients was correlated with infarct time. |
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| Keywords: | neuroglobin acute cerebral infarction onset time morbidity infarct size neurological impairment score |
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