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| 结核病患者外周血CD4+记忆T细胞亚群的检测及意义 | |
| 引用本文： | 朱建东,郑碎珠,张品南,叶玲丽,朱伦. 结核病患者外周血CD4+记忆T细胞亚群的检测及意义[J]. 放射免疫学杂志, 2011, 24(5): 567-570 |
| 作者姓名： | 朱建东 郑碎珠 张品南 叶玲丽 朱伦 |
| 作者单位： | 1. 浙江省乐清市第三人民医院,325604 2. 浙江省温州市第三人民医院,325000 |
| 摘 要： | 目的:探讨结核病患者外周血总CD4+T细胞及抗原特异性记忆T细胞的产生及分布规律,了解记忆T细胞在结核病发病中的作用.方法:以荧光标记的抗CD4、CCR7、CD45RA三种抗体共染色,用流式细胞仪检测结核病患者外周血总CD4+记忆T细胞,以荧光标记的抗人CD4、CD154、CCR7、CD45RA四种抗体共染色,检测结核... |
| 关 键 词： | 结核病 T淋巴细胞亚群 记忆细胞 |
Detection and Significance of CD4+ Memory T Cell Subsets in Patients with Tuberculosis |
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| Zhu Jian-dong,Zheng Sui-zhu,Zhang Pin-nan,et al.. Detection and Significance of CD4+ Memory T Cell Subsets in Patients with Tuberculosis[J]. Journal of Radioimmanology, 2011, 24(5): 567-570 | |
| Authors: | Zhu Jian-dong Zheng Sui-zhu Zhang Pin-nan et al. |
| Affiliation: | Zhu Jian-dong,Zheng Sui-zhu,Zhang Pin-nan,et al. Yueqing Third People's Hospital(325604),Yueqing(325604),China |
| Abstract: | Objective To study the production and distribution of total CD4+ memory T cells and antigen-specific memory T cell from patients with tuberculosis and to realize the role of memory T cells in the pathogenesis of tuberculosis.Methods Total CD4+memory T cells in the peripheral blood of patients with tuberculosis were detected by labeling with CD4,CCR7 and CD45RA fluorescence-antibodies and analyzing with flow cytomety.Mycobacterial antigen-specific memory T cells were detected by labeling with CD4,CD154,CCR7 ... |
| Keywords: | Tuberculosis T-lymphocyte subset Memory T cells |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |