糖尿病性白内障术前1d和术后1d黄斑厚度及容积的变化

目的：探讨糖尿性白内障术前1d及术后1d黄斑分区厚度及容积变化规律。

方法：选择50例需要行超声乳化白内障摘除并人工晶状体植入术的2型糖尿病患者(非增殖期视网膜病变)，其术眼术前1d与术后1d分别作为观察和对照。 采用频域光学相干断层扫描(OCT)检查黄斑区，观察黄斑分区视网膜厚度、容积及黄斑区总容积的光学相干断层扫描变化情况。

结果：所有患者OCT均未见黄斑区视网膜形态异常。黄斑内环A、中环B、外环C视网膜各个分区厚度及容积分布不均，容积呈现由内向外的盆地分布。术后1d，黄斑区九分区中，B2、C2、C3、C4分区黄斑平均厚度较术前1d增厚，差异有统计学意义(P<0.05)。术后1d黄斑中心凹1mm 视网膜平均厚度(A)与术前1d相比无显著变化，差异无统计学意义(P>0.05)。术后1d，A、B4、C1、C2、C4分区黄斑平均容积较术前1d增加，差异有统计学意义(P<0.05)。术后1d总容积较术前1d比较差异无统计学意义(P>0.05)。

结论：糖尿病性白内障手术构成黄斑厚度及容积变化的影响因素。

Macular thickness and macular volume measurements on 1d both preoperatively and postoperatively for diabetic cataract

AIM:To investigate the change regulation of macular thickness and volume on 1d preoperatively and 1d postoperatively in diabetic cataract patients affected by cataract surgery using stratus optical coherence tomography(OCT).

METHODS: Totally 50 patients with type 2 diabetes mellitus(non proliferative retinopathy)requiring phacoemulsification and intraocular lens implantation were enrolled. This study was designed as self-controlled of 1d preoperatively and 1d postoperatively eyes. OCT was used to examine the macular thickness, volume, and total macular volume.

RESULTS: No abnormal retinal morphology of macular region was found in any of the patients by OCT. Maldistribution was observed in the thickness and volume of the macular inner ring A, central B and outer ring C. The volume presented a basin distribution from the interior to the exterior. At 1d after surgery, of the nine compartment of the macular region, the macular mean B2, C2, C3 and C4 was thicker than that 1d before surgery. And the difference was statistically significant(P<0.05). There was no significant difference in the mean retinal thickness of macular within 1mm(A)at 1d before and after surgery(P>0.05). Moreover, at 1d after operation, the average volume of macula in A, B4, C1, C2 and C4 increased significantly compared with that at 1d before operation(P<0.05), whereas there were no obvious changes in total volume after operation than before(P>0.05).

CONCLUSION: Diabetic cataract surgery affects the macular thickness and volume.