急性心肌缺血对心脏电稳定性的影响

目的 应用长程晚电位及长程QT间期变异技术分别从心室除极、复极的角度探讨冠状动脉急性缺血对心电稳定性的影响。方法 选择我院住院的心绞痛频繁发作的冠心病患者47例，佩戴数字化Hoher记录仪，选取心绞痛发作时及症状缓解6h后的长程晚电位及QT间期变异各项参数指标，每一指标选取临近时间段的三个数值，取其均数用做统计数据。结果 在心绞痛发作时及症状恢复后，晚电位及QT间期变异各项参数均显示明显变化，差异有统计学意义（P〈0．05）。结论 冠状动脉血流情况与心电稳定性指标显著相关，短暂心肌缺血时心室除极、复极指标也有显著变化，其敏感性高于普通心电图，可以成为评价无创冠状动脉缺血事件的有益补充。

Influence of acute myocardial ischemia on myocardial electrophysiological stability

Objective To study the electrophysiological correlation of ventricular depolarization(detected by signalaveraged ECG,VLP)and repolarization(detected by QT interval variability,QTV)with transient myocardial ischemia.Methods Digital Holter ECG was recorded in 47 patients with angina pectoris.To analyse the parameters of VLP and QTV during transient myocardial ischemia and 6 hours after angina by the Holter recorder.We chose three random continuous times,the parameter of VLP and QTV was determined in triplicate and averaged.Results The parameters of VLP and QTV showed significant difference during transient myocardial ischemia and 6 hours after angina.Conclusions Myocardial electrophysiological stability correlated with coronary blood flow.There was significant diversity of ventricular depolarization and repolarization in the period of transient myocardial ischemia,which provide a new valuable noninvasive diagnostic method for clinic.