冠状动脉粥样硬化危险因素的Logistic回归分析

目的探讨常见影响因素对冠状动脉粥样硬化形成的危险性，为临床防治提供科学依据。方法选择2005年6月-2009年1月入住我院的疑诊冠心病并行CT血管成像（CTA）检查的患者276例，根据冠脉CTA结果将其分为正常、轻度粥样硬化及冠心病三组，用卡方检验和多元Logistic回归分析对其常见影响因素进行分析。结果单因素回归分析显示：年龄（X^2=14．394，P=-0．006）、高血压（X^2=6．445，p=0．040）、总胆固醇（X^2=8．464，P=0．015）、甘油三酯（X^2=7．084，P=-0．029）、低密度脂蛋白（X^=2=6．399，P=0.041）对冠状动脉粥样硬化形成有影响；多元logistic回归分析后发现年龄（Wald=14．433，P=-0．000）、吸烟（waid=7．425，P=-0．007）及总胆固醇（Wald=4．637，P=0．031）对冠状动脉粥样硬化形成的影响较其它因素更大。结论本研究发现年龄、吸烟及总胆固醇是影响冠状动脉粥样硬化的主要危险因素，针对可控危险因素给予积极有效的控制，为患者提供个性化健康教育，改变不良的行为和生活方式，提高治疗依从性，能更有效地预防冠心病的发生。

Coronary atherosclerosis Logistic regression analysis of risk factors for nursing enlightenment

Objective Depth analysis of common factors on the formation of coronary atherosclerosis risk, Providing a scientific basis for clinical prevention and treatment.Methods Selected in June 2005 ～ January 2009 stay at our hospital diagnosed as coronary heart disease concurrent CTA examined 276 cases of patients, according to the results of coronary CTA will be divided into normal, mild atherosclerosis and coronary heart disease 3 groups, using chi-square test and Logistic regression analysis of multiple factors affecting their common-depth analysis. Results The results of univariate regression analysis showed that: age (χ~2=14.394, P= 0.006), hypertension (χ~ 2 = 6.445, P=0. 040), total cholesterol (x~2 = 8.464, P= 0.015), triglycerides (χ~2 = 7.084, P=0.029), low-density lipoprotein (χ~2= 6.399, P= 0.041) on the formation of coronary atherosclerosis affected; multiple logistic regression analysis showed that age (Wald = 14.433, P= 0.000), smoking (Wald = 7. 425, P= 0.007) and total cholesterol (Wald = 4.637, P= 0.031) of coronary atherosclerosis than other factors affecting the formation of a greater.Conclusion This study found that age, smoking and total cholesterol, affecting the coronary atherosclerosis of the major risk factors, controllable risk factors for positive and effective control, in order to provide patients with personalized health education to change unhealthy behavior and lifestyles, to improve treatment compliance would be more effective in preventing the occurrence of coronary heart disease.