非剥脱1550nm铒玻璃点阵激光治疗活动性痤疮及痤疮瘢痕临床疗效观察

目的：观察非剥脱1550nm铒玻璃点阵激光治疗活动性痤疮及痤疮凹陷性瘢痕的临床疗效及安全性。方法：应用非剥脱性1550nm铒玻璃点阵激光治疗中重度痤疮患者25例，其中16例表现为活动性痤疮皮损（粉刺、丘疹、脓疱、结节）合并痤疮后凹陷性瘢痕，3例为痤疮瘢痕不伴活动性皮损，6例为活动性皮损不伴瘢痕形成。治疗1-3次，每次间隔3-4周，于末次治疗1个月后观察疗效。结果：活动性皮损22例，痊愈2例（9．1％）、显效14例（63．6％）、有效6例（27．3％）、无效或恶化0例（O％），总有效率为72．7％；痤疮凹陷性瘢痕19例，痊愈2例（10．5％）、显效10例（52．6％）、有效7例（36．8％）、无效或恶化0例（0％），总有效率为63．2％。且随着治疗次数的增加疗效逐步提高。术后仅出现轻度红肿，平均2-3天消退，均无色素沉着、水疱等不良反应，无1例恶化，患者满意率达840。结论：非剥脱1550nm铒玻璃点阵激光治疗活动性痤疮及痤疮后凹陷性瘢痕均有显著疗效，且安全、不艮反应轻，患者满意率高。

Evaluation of clinical improvement in active acne and acne scars treated with the nonablative 1550nm erbium-glass fractional laser

Objective To observe the clinical efficacy and safety of the non-ablative 1550nm erbium-glass fractional laser in treating active ache （comedo, papule, pustule and nodule） and atrophic ache scars. Methods A non-ablative 1550nm erbium-glass fractional laser was used to treat 25 patients （16 patients with both active acne and acne scars, 3 patients only with acne scars, 6 patients only with active ache） one to three times at 3 or 4-week intervals. The clinical efficacy was evaluated 1 month after the final treatment. Results About the improvement of active ache in 22 patients with active acne, 2 cases（9.1%）was cured, 14 cases（63.6%）were improved significantly, 6 cases（27.3%）were improved, 0 cases （0%）was ineffective, the total effective rate was 72.7%. About the improvement of acne scars in 19 patients with ache scars, 2 cases （10.5%）was cured, 10 cases （52.6%）were improved significantly, 7 cases （36.8%）were improved, 0 cases （0%）was ineffective,the total effective rate was 63.2%. And the efficacy of both active acne and acne scars gradually increased with the increase of treatment sessions. The main side effect was postoperative mild erythema and edema persisting only two to three days. Side effects such as postoperative hyperpigmentation and vesicle were not observed,and no case occurred deterioration.The satisfaction rate was 84%. Conclusion non-ablative 1550nm erbium- glass fractional laser was safe and effective in treating moderate to severe ache and atrophic acne scars.