急诊经皮冠状动脉介入治疗对急性心肌梗死血浆脑钠肽水平的影响观察

目的探讨急诊经皮冠状动脉介入治疗对急性心肌梗死血浆脑钠肽水平的影响。方法选择我院急性心肌梗死患者110例,分为观察组和对照组。观察组实施急诊经皮冠状动脉介入治疗,对照组为静脉溶栓治疗。同时选择健康者作为正常组。测定观察组和对照组入院时及入院后不同时刻血浆脑钠肽水平,测定正常组血浆脑钠肽水平。结果观察组和对照组入院时的血浆脑钠肽水平均高于正常组,差异有统计学意义(P<0.05);观察组入院后24 h、入院后72 h、入院后第7天的血浆脑钠肽水平分别低于对照组同时刻血浆脑钠肽水平,差异有统计学意义(P<0.05)。结论急诊经皮冠状动脉介入治疗能够降低急性心肌梗死患者血浆脑钠肽水平,具有重要临床意义。

Observation of Plasma Brain Natriuretic Peptide Level of Emergency Percutaneous Coronary Intervention on Acute Myocardial Infarction

Objective To explore the effect of plasma level of brain natriuretic peptide of emergency percutaneous coronary intervention on acute myocardial infarction. Methods 110 cases with with acute myocardial infarction were selected and divided into observation group and control group. The observation group received percutaneous coronary intervention, the control group received Intravenous thrombolytic therapy. At the same time 30 healthy volunteers was selected as normal group.Plasma brain natriuretic peptide levels were measured in the normal group、the observation group and the control group. Results Plasma brain natriuretic peptide levels in the observation group and the control group admission was higher than that in the normal group, the difference was statistically significant （P〈0.05）;Plasma brain natriuretic peptide levels in observation group at the time of the 24 hours, 72 hours and seventh day after admission was lower than those in the control group at different time, the difference was statistically significant （P〈0.05）. Conclusion Eemergency percutaneous coronary intervention on acute myocardial infarction can reduce the level of plasma brain natriuretic peptide, and it has important clinical significance.