尿微量清蛋白检测对诊断早期糖尿病肾病的临床意义

目的：探讨尿微量清蛋白检测对诊断早期糖尿病肾病的临床意义。方法回顾性分析2011年8月至2013年2月化州市中医院收治的50例糖尿病肾病患者（观察组）和50例健康体检者（对照组）的临床资料。结果观察组患者尿微量清蛋白含量和阳性率均明显比对照组高，差异有统计学意义（P＜0．05），但观察组男性患者和女性患者阳性率差异无统计学意义（ P＞0．05）；病程大于12年患者的尿微量清蛋白含量和阳性率均明显比病程0～6、＞6～12年患者高，差异有统计学意义（ P＜0．05），且病程0～6、＞6～12年患者尿微量清蛋白和阳性率比较，差异均有统计学意义（P＜0．05）。结论尿微量清蛋白检测能够为临床早期发现、诊断和治疗糖尿病肾病提供有效依据。

Clinical significance of urinary microalbumin in the diagnosis of early diabetic nephropathy

Objective To investigate the clinical significance of urinary microalbumin in the diagnosis of early diabetic nephropathy .Methods Clinical data of 50 patients with diabetic nephropathy treated in this hospital from August 2011 to February 2013 were retrospectively analyzed .Results Level and positive rate of urinary microalbu-min in observation group were significantly higher than that of the control group （P〈0 .05） ,but there was no signifi-cant difference of positive rate between men and women in observation group （P〉0 .05） .Urinary microalbumin con-centration and positive rate of patients with disease course at least 12 years were significantly higher than patients with disease course less than 12 years （P〈0 .05） ,and but the differences between patients with disease course of 0-6 years and 6-12 years were significant （P〈0 .05） .Conclusion Detection of urinary microalbumin could provide ef-fective basis for the early diagnosis and treatment of diabetic nephropathy .