Identification of aldo-keto reductases as NRF2-target marker genes in human cells期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Identification of aldo-keto reductases as NRF2-target marker genes in human cells

Authors:	Kyeong-Ah Jung Bo-hyun Choi Chang-Won Nam Mingu Song Sang-Tae Kim Joo Young Lee Mi-Kyoung Kwak

Institution:	1. College of Pharmacy, The Catholic University of Korea, Bucheon, Gyeonggi-do 420-743, Republic of Korea;2. College of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do 712-749, Republic of Korea

Abstract:

Keywords:	AKR aldo-keto reductase shNRF2 NRF2 knockdown cell line sc nonspecific control cell line ARE antioxidant-response element ROS reactive oxygen species GSH glutathione NQO1 NAP(D)H: quinone oxidoreductase-1 GST glutathione S-transferase GCLC catalytic subunit of γ-glutamate cysteine ligase GCLM modulatory subunit of γ-glutamate cysteine ligase SOD superoxide dismutase GSR glutathione reductase G6PD glucose-6-phosphate-1-dehydrogenase PRDX peroxiredoxin TXNRD thioredoxin reductase UGT UDP glucuronosyltransferase EPHX epoxide hydrolase FTH ferritin heavy polypeptide ALDH aldehyde dehydrogenase SULT sulfotransferase MRP multidrug resistance-associated protein HMOX-1 heme oxygenase-1 MTT 3-(4 5-dimethylthiazol-2-yl)-2 5-diphenyltetrazolium bromide DMSO dimethyl sulfoxide SFN sulforaphane t-BHQ tert-butylhydroquinone CA cinnamic aldehyde
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