| 他汀类和烟酸类降脂药物联合应用治疗心血管疾病 |
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| 引用本文： | 冉宇,刘君玲,张强. 他汀类和烟酸类降脂药物联合应用治疗心血管疾病[J]. 中国心血管杂志, 2007, 12(1): 78-80 |
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| 作者姓名： | 冉宇 刘君玲 张强 |
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| 作者单位： | 天津市第四中心医院ICU,天津,300140 |
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| 摘 要： | 单独使用他汀类降脂药治疗时,许多患者的血浆脂蛋白达不到治疗目标,尤其是在多项血脂不正常的患者中,他汀类只能轻度的增高高密度脂蛋白(HDL-C):一种独立预测冠心病的因素和轻度的降低甘油三酯(TG)的作用。烟酸对增高HDL和降低TG有明显的药理作用。他汀类和烟酸类合用可以帮助患者控制低密度脂蛋白胆固醇(LDL-C)和升高HDL-C。
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| 关 键 词： | 烟酸类 他汀类 冠心病 高密度脂蛋白 低密度脂蛋白胆固醇 |
| 文章编号： | 1007-5410(2007)01 |
| 修稿时间： | 2006-04-14 |
Combination niacin and statin therapy in primary and secondary prevention of cardiovascular disease |
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| RAN Yu,LIU Jun-ling,ZHANG Qiang. Combination niacin and statin therapy in primary and secondary prevention of cardiovascular disease[J]. Chinese Journal of Cardiovascular Medicine, 2007, 12(1): 78-80 |
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| Authors: | RAN Yu LIU Jun-ling ZHANG Qiang |
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| Affiliation: | Intensive Care Unit, Forth Central Hospital of Tianjin , Tianjin 300140, China |
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| Abstract: | Statin monotherapy may not be sufficient to reach serum lipid goals in many patients,especially in those with combined lipid abnormalities.Statins cause only a modest increase in high-density lipoprotein cholesterol(HDL)-an established independent protective factor for coronary heart disease(CHD) and a modest decrease in triglycerides(TG).Niacin is an effective pharmacologic agent for increasing HDL,as well as lowering TG.Used in combination with a statin,niacin provides an aption to help patients decrease HDL goals. |
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| Keywords: | Niacin Statin Coronary heart disease High-density lipoprotein Low-density lipoprotein cholesterol |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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