参苓白术散加减对慢性阻塞性肺疾病患者呼吸机待机时间的影响分析

目的分析参苓白术散加减对慢性阻塞性肺疾病患者呼吸机待机时间的影响。方法 120例慢性阻塞性肺疾病患者作为研究对象,随机分为对照组和观察组,各60例。对照组患者接受机械通气治疗,观察组患者在对照组基础上加用参苓白术散加减治疗。观察对比两组患者治疗前后肺功能情况、机械通气时间、住院时间以及临床治疗效果。结果治疗前,两组患者的动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)、用力肺活量(FVC)、第1秒用力呼气容积(FEV1)水平对比,差异无统计学意义(P>0.05);治疗后,观察组患者的PaO2、FVC及FEV1水平分别为(85.3±5.9)mm Hg、(2.9±0.4)L及(2.6±0.4)L,均明显高于对照组的(74.7±4.8)mm Hg、(2.4±0.3)L及(1.8±0.3)L, PaCO2水平(32.7±4.1)mm Hg明显低于对照组的(41.3±3.6)mm Hg,差异具有统计学意义(P<0.05)。观察组患者的机械通气时间及住院时间分别为(75.15±3.27)h、(7.69±1.03)d,均明显短于对照组的(116.49±6.73)h、(10.45±1.06)d,差异具有统计学意义(P<0.05)。观察组患者临床治疗总有效率98.33%明显高于对照组的85.00%,差异具有统计学意义(P<0.05)。结论在慢性阻塞性肺疾病患者接受机械通气治疗的过程中,加用参苓白术散加减能有效缩短呼吸机待机时间,值得在临床治疗中推广。

Analysis of the effect of addition and subtraction of Shenling Baizhu powder on the standby time of ventilator in patients with chronic obstructive pulmonary disease

Objective To analyze the effect of addition and subtraction of Shenling Baizhu powder on the standby time of ventilator in patients with chronic obstructive pulmonary disease. Methods A total of 120 patients with chronic obstructive pulmonary disease as study subjects were randomly divided into control group and observation group, with 60 cases in each group. The control group was treated by mechanical ventilation, and the observation group was treated by addition and subtraction of Shenling Baizhu powder on the basis of the control group. The pulmonary function before and after treatment, duration of mechanical ventilation, hospitalization time and clinical effect between the two groups was observed and compared. Results Before treatment, there was no statistically significant difference in arterial oxygen partial pressure(PaO2), arterial carbon dioxide partial pressure(PaCO2), forced vital capacity(FVC), forced expiratory volume in the first second(FEV1) between the two groups(P>0.05). After treatment, the levels of PaO2, FVC and FEV1 were(85.3±5.9) mm Hg,(2.9±0.4) L and(2.6± 0.4) L in the observation group, which were obviously higher than(74.7±4.8) mm Hg(1 mm Hg=0.133 kPa),(2.4±0.3) L and(1.8±0.3) L in the control group, and PaCO2(32.7±4.1) mm Hg was obviously lower than(41.3±3.6) mm Hg in the control group. Their difference was statistically significant(P<0.05). The duration of mechanical ventilation and hospitalization time were(75.15±3.27) h and(7.69±1.03) d in the observation group, which were obviously shorter than(116.49±6.73) h and(10.45±1.06) d in the control group, and their difference was statistically significant(P<0.05). The total effective rate of clinical treatment 98.33% in the observation group was obviously higher than 85.00% in the control group, and the difference was statistically significant(P<0.05). Conclusion In the course of mechanical ventilation treatment for patients with chronic obstructive pulmonary disease, the addition and subtraction of Shenling Baizhu powder can effectively shorten the standby time of ventilator, which is worth popularizing in clinical treatment.