Investigation into cases of hepatitis of unknown aetiology among young children,Scotland, 1 January 2022 to 12 April 2022 |
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| Authors: | Kimberly Marsh Rachel Tayler Louisa Pollock Kirsty Roy Fatim Lakha Antonia Ho David Henderson Titus Divala Sandra Currie David Yirrell Michael Lockhart Maria K. Rossi Nick Phin |
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| Affiliation: | 1.Public Health Scotland, Glasgow, United Kingdom; 2.Department of Paediatric Gastroenterology, Hepatology and Nutrition, Royal Hospital for Children, Glasgow, Glasgow, United Kingdom; 3.Department of Paediatric Infectious Diseases and Immunology, Royal Hospital for Children, Glasgow, United Kingdom; 4.Medical Research Council-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom |
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| Abstract: | ![]()
On 31 March 2022, Public Health Scotland was alerted to five children aged 3–5 years admitted to hospital with severe hepatitis of unknown aetiology. Retrospective investigation identified eight additional cases aged 10 years and younger since 1 January 2022. Two pairs of cases have epidemiological links. Common viral hepatitis causes were excluded in those with available results. Five children were adenovirus PCR-positive. Other childhood viruses, including SARS-CoV-2, have been isolated. Investigations are ongoing, with new cases still presenting. |
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| Keywords: | Hepatitis of unknown aetiology outbreak paediatric patients adenovirus public health response |
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