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Perioperative evaluation of glycaemic status in neck dissection: a retrospective analysis at a single hospital centre
Affiliation:1. Department of Anaesthesiology and Intensive Care Medicine, Sveti Duh University Hospital, Zagreb, Croatia;2. School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia;1. Department of Maxillofacial, Plastic, Reconstructive and Cosmetic Surgery, Nancy University Hospital, Nancy, France;2. University of Lorraine, Nancy, France;1. Department of Oral and Maxillofacial Surgery, İstanbul University Faculty of Dentistry, İstanbul, Turkey;2. Department of Basic Medical Sciences, İstanbul University Faculty of Dentistry, İstanbul, Turkey;3. Department of Metallurgical and Materials Engineering, İstanbul Technical University, İstanbul, Turkey;1. Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University, Egypt;2. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Thamar University, Yemen;3. Department of Prosthodontics, Faculty of Odontology, Malmö University, Sweden;1. Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People''s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China;2. Discipline of Oral and Maxillofacial Surgery, Alexandra Hospital, Jurong Health System, Singapore;3. Department of Oral Pathology, Ninth People''s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China;1. Department of Dental Materials and Prosthodontics, Araçatuba Dental School, UNESP, Araçatuba, São Paulo, Brazil;2. Department of Production Engineering, Polytechnic School, USP, São Paulo, Brazil
Abstract:Diabetes mellitus is generally considered a risk factor for impaired wound healing. This study aimed to evaluate the glycaemic status of patients undergoing neck dissection and describe its impact on postoperative outcomes, especially wound healing. A retrospective analysis was performed of the preoperative, intraoperative, and postoperative glycaemic data obtained from the medical charts of 60 adult patients who had undergone 64 neck dissections. Nine of the 64 procedures were performed in diabetic patients (14.1%). The average glucose values were: preoperative 5.99 ± 1.25 mmol/l, intraoperative 8.90 ± 2.62 mmol/l, and postoperative 10.01 ± 2.49 mmol/l. All registered preoperative hyperglycaemia cases (eight cases) were diabetic. Postoperative insulin therapy was done in 14 procedures (21.9%). Wound healing complications were found in five patients (7.8%); there was no wound infection. There was no association of wound healing complications with preoperative diabetic status (P = 1.000), preoperative glucose control (P = 1.000), preoperative (P = 0.469), intraoperative (P = 0.248), and postoperative (P = 0.158) glucose values, or with postoperative glucose control (P = 0.577). These data do not support the association of stress-induced hyperglycaemia or diabetes mellitus with postoperative wound healing problems in neck dissection.
Keywords:diabetes mellitus  hyperglycaemia  wound healing  surgical site infection  neck dissection.
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